Revista Farmespaña Industrial Enero - Febrero 2025

peratura, la disponibilidad del oxígeno… (figura 5). En resumen, la inactivación de residuos con principios ac- tivos en la industria farmacéu- tica es fundamental para evitar la contaminación del medio ambiente y proteger la salud pública. Es muy importante es- tudiar cada caso al detalle y ver cuál es la tecnología que mejor se ajusta según el compuesto que se esté formulando. De este modo, no solo se asegura el cumplimiento de las nor- mativas ambientales, sino que también se promueve la soste- nibilidad, al evitar la liberación de contaminantes persistentes (Tabla 1) ◉ Bibliografia • Veolia (2020). Pharma Guide: Wastewater Management in the Pharmaceutical Industry. Veolia_Phar- ma_Guide_Wastewater_2020_HR_ With_Links_0.pdf • Rhone, J (2020, 19 de Febrero). Trea- ting active pharmaceutical ingredients in manufacturing wastewater. Water Techonolgy. Recuperado de: https:// www.watertechonline.com/wastewa- ter/article/14167403/treating-acti- ve-pharmaceutical-ingredients-in-ma- nufacturing-wastewater • Fakhri B., M. S., Ghassemi Barghi, N., Moradnia Mehdikhanmahaleh, M., Raeis Zadeh, S. M. M., Mousavi, T., Rezaee, R., … Abdollahi, M. (2024). Pharmaceutical wastewater toxicity: An ignored threat to the public health. Sustainable Environment, 10 (1). https://doi.org/10.1080/27658511.20 24.2322821 • Guo, Y & Qi, P & Liu, Y. (2017). A Review on Advanced Treatment of Pharma- ceutical Wastewater. IOP Conference Series: Earth and Environmental Science. 63. 012025. 10.1088/1755- 1315/63/1/012025. • (n.d). Who Guidance on waste and wastewater management in pharmaceutical manufacturing with emphasis on antibiotic production. waste-and-wastewater-mana- gement-in-pharma-manufactu- ring---pub-consult-231214.pdf • Das, M., Bhattacharyya, I., Chattopad- hyay, S., Sengupta, S., Chowdhury, A. S., Sikdar, P., Mishra, D., Chakraborty, S., Biswas, S., Dasgupta, D., & Nag, M. (2024). Pharmaceutical waste water treatment methods for small-scale industries. International Journal of Pharmaceutical Sciences Review and Research. https://doi.org/10.47583/ ijpsrr.2024.v84i07.018 • (n.d). Non-Incineration Treatment and Disposal of Healthcare Waste. Module 2: The Healthcare Waste Management System • Canga-Rodríguez, J (n.d.). Modern wastewater treatment solutions in a state-of-the-art pharmaceutical production environment. EnviroChe- mie GmbH. Recuperado de: Microsoft Word - EnviroChemie_EWA 2012_Ar- tikel.docx • Kundan Samal, Saswat Mahapatra, Md Hibzur Ali, Pharmaceutical wastewater as Emerging Contamintats (EC): Treatment technologies, impact on environment and human health, Ener- gy Nexus, Volume 6, 2022, Volume 6, 2022, 10076, ISSN 2772-4271. https:// doi.org/10.1016/j.nexus.2022.100076. • Reddy, B. V., Sandeep, P., Ujwala, P., Navaneetha, K., & Ramana Reddy, K. V. (2014). Water treatment process in pharma industry: A review. Internatio- nal Journal of Pharmacy and Biological Sciences, 4(2), 7-18. Recuperado de ht- tps://ijpbs.com/ijpbsadmin/upload/ ijpbs_536f2f44ced28.pdf • Process at a wastewater treatment plant (HHE Report No. 2014-0052- 3320). National Institute for Occupatio- nal Safety and Health (NIOSH), Centers for Disease Control and Prevention (CDC). Recuperado de https:// www.cdc.gov/niosh/hhe/reports/ pdfs/2014-0052-3320.pdf • Van Vaerenbergh, B., Willemarck, N., Brosius, B., Leunda, A., Baldo, A., & Do Thi, C. D. (2012). Effluent decontami- nation systems: An overview. SBB. Recuperado de https://www.biosafety . be/sites/default/files/2012_effluent- deconsystems_sbb_2505_58.pdf • Niu, X., Song, X., Li, P., & Wang, Z. (2020). A review of the application of renewable energy in the treatment of pharmaceutical wastewater. Energies, 17(17), 4447. https://doi.org/10.3390/ en17174447 • Pharmaceutical Networking. (n.d.). Thermal wastewater inactivation and sterilisation. Recuperado de https:// www.pharmaceutical-networking. com/thermal-wastewater-inactiva- tion-and-sterilisation/ • Neutralization Process In Wastewater Treatment - Water & Wastewater: Your Source for Water Clarity • Water & Wastewater. (n.d.). Neu- tralization process in wastewater treatment. Recuperado de https:// www.waterandwastewater.com/ neutralization-process-in-wastewa- ter-treatment/ • Aldeguer Esquerdo, A., Varo Galvañ, P. J., Sentana Gadea, I., & Prats Rico, D. (2021). Tratamiento de fármacos presentes en aguas mediante ozono. En Congreso Digital de AEDyR – 2021 (Ref. AedyrDIG21-25, ISBN 978-84-09-27519-9). Recuperado de https://aedyr.com/wp-content/ uploads/2021/04/DIG21-25.pdf • Navidpour, A.H.; Ahmed, M.B.; Zhou, J.L. (2024), Photocatalytic Degradation of Pharmaceutical Residues from Water and Sewage Effluent Using Different TiO2 Nanomaterials. Na- nomaterials, 14 (2), 135. https://doi. org/10.3390/nano14020135 • Gonzaga, I.M.D.; Almeida, C.V.S.; Mascaro, L.H. (2023). A critical review of photo-based advanced oxidation processes for pharmaceutical degra- dation. Catalysts, 13 (2), 221. https://doi. org/10.3390/catal13020221 • Alvarenga Junior, R. de, & Lajarim Car- neiro, L. (2019). Chemometrics Approa- ches in Forced Degradation Studies of Pharmaceutical Drugs. Molecules, 24 (20), 3804. https://doi.org/10.3390/ molecules24203804 • Bampos, G.; Petala, A., & Frontistis, Z. (2021). Recent Trends in Pharmaceuti- cals Removal fromWater Using Elec- trochemical Oxidation Processes. En- vironments, 8 (8), 85. https://doi. org/10.3390/environments8080085 • ISPE. (2020). Industry perspective: Bio- remediation of pharmaceuticals. Phar- maceutical Engineering, March-April 2020. Recuperado de https://ispe. org/pharmaceutical-engineering/ march-april-2020/industry-perspecti- ve-bioremediation-pharmaceuticals • Yisau, Y. S., Al-Makishah, N. H., & Barakat, M. A. E. F. (2024). Micro- bial degradation of paracetamol in pharmaceutical wastewater: A review. Journal of Environmental Sciences, 31, 47-56. https://doi.org/10.3844/ ajessp.2024.31.47 • Wastech Engineering. (n.d.). BioKill. Recuperado de https://wastechengi- neering.com/biokill.html • Mishra, R., Singh, R. K., & Yadav, S. (2023). Sustainable removal of pharmaceutical contaminants from wastewater using advanced treatment technologies. Environmental Science and Pollution Research. https://doi. org/10.1007/s13762-023-04880-2 Tabla 1. sostenibilidad 28 FARMESPAÑA INDUSTRIAL · ENE/FEB 25

RkJQdWJsaXNoZXIy OTAxNDYw