Revista Farmespaña Industrial Mayo Junio 2026

Aplicaciones de la inteligencia artificial en farmacovigilancia La farmacovigilancia (FV) tiene como objetivo identificar, evaluar, comprender y prevenir riesgos asociados al uso de medicamentos a lo largo de todo su ciclo de vida. En la práctica actual, esta disciplina se enfrenta a un crecimiento sostenido del volumen de información y una diversidad de fuentes cada vez mayor. A la notificación espontánea se han incorporado la literatura científica, información procedente de entornos clínicos y otras fuentes complementarias. Este entorno de datos, con coexistencia de información estructurada y no estructurada, incrementa las exigencias de capacidad analítica, agilidad en la revisión y consistencia metodológica. JOSÉ LUIS GIL DÍAZ (PV OFFICER TRAINEE, PVPHARM) , MARÍA DEL CARMEN GARCÍA ALCARAZ (PV OFFICER, PVPHARM) , MAYTE ALONSO HERRERAS (HEAD OF OPERATIONS, PVPHARM), JOSÉ ALBERTO AYALA ORTIZ (CEO, PVPHARM 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n%"# ](2D"6^# 3'2&2# &2+$%$*(2# -/,/# $%+/*,"0 -$4%#3*/-2&2%)2#&2#'%"#/#8"*$"(#+'2%)2(#H'2# ('7$2*2#'%"#3/($562#%'28"#"(/-$"-$4%#-"'("6# i/# '%# %'28/# "(32-)/# &2# '%"# "(/-$"-$4%# :"# -/%/-$&"j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iEMj# 3'2&2# -/%)*$0 5'$*# "# /3)$,$;"*# 3"*)2(# &2# 2()2# -$-6/?# 2(320 -$"6,2%)2# -'"%&/# 6"# -"*7"# &2# $%+/*,"-$4%# -/,3*/,2)2# 6"# 2+$-$2%-$"# /# 6"# '%$+/*,$&"&# &2# 6/(# 3*/-2(/(# ,"%'"62(<# T"N/# 26# ).*,$%/# EM# (2# "7*'3"%# ).-%$-"(# F2)2*/7.%2"(?# 2%)*2# 266"(# 26# "3*2%&$;"N2# "')/,G)$-/# i,"-F$%2# 62"*%$%7?#X!j?#26#3*/-2(",$2%)/#&26#62%7'"N2# %")'*"6# iL!mj# :?# ,G(# *2-$2%)2,2%)2?# ,/&20 6/(#72%2*")$8/(#&2# 62%7'"N2<#=%#+"*,"-/8$7$0 6"%-$"?#('#2%-"N2#,G(#F"5$)'"6#2(#-/,/#$%)20 6$72%-$"#"',2%)"&"_#($()2,"(#H'2#"3/:"%#6"# 2()*'-)'*"-$4%?# 3*$/*$;"-$4%# /# 51(H'2&"# &2# $%+/*,"-$4%?# ,"%)2%$.%&/(2# 6"# &2-$($4%# +$0 %"6#5"N/#('32*8$($4%#F',"%"?#2(32-$"6,2%0 )2#2%#)"*2"(#-/%#'%#3/)2%-$"6#$,3"-)/#(/5*2# 6"#(27'*$&"&#&26#3"-$2%)2< k2(&2# '%"# 32*(32-)$8"# /32*")$8"?# 6"(# "36$0 -"-$/%2(#,G(#-/%(/6$&"&"(#(2#/*$2%)"%#"#)"0 *2"(#28"6'"562(#/5N2)$8",2%)2#:#-/%#'%#"6)/# -/,3/%2%)2# *232)$)$8/<# =%# 2()2# G,5$)/# (2# ($)1"%#6"#2()*'-)'*"-$4%#&2#$%+/*,"-$4%#-/%0 )2%$&"# 2%# %"**")$8"(# &2# $%+/*,2(# $%&$8$&'"0 62(#&2# (27'*$&"&# iEQ\[(j?# 6"#%/*,"6$;"-$4%# :# -/&$+$-"-$4%# )2*,$%/647$-"?# 6"# &2)2--$4%# &2# &'36$-"&/(?# 26# )*$"N2# :# 3*$/*$;"-$4%# &2# -"(/(# :# (2D"62(# 3"*"# *28$($4%# 2>32*)"?# :# 26# -*$5"0 &/# &2# 6$)2*")'*"# 3"*"# $&2%)$+$-"*# 3/)2%-$"62(# 282%)/(#"&82*(/(#*2628"%)2(<#k2#+/*,"#-/,0 362,2%)"*$"?# 6"# "')/,")$;"-$4%# */54)$-"# &2# 3*/-2(/(# i[LMj# 32*,$)2# "')/,")$;"*# 3"(/(# 3*/-2&$,2%)"62(# :# )*";"562(?# $%)27*G%&/(2# -/%# L!meX!# -'"%&/# 6"# $%+/*,"-$4%# &2# 2%0 )*"&"# 2(# %/# 2()*'-)'*"&"<# M($,$(,/?# (2# 2>0 36/*"%# 2%+/H'2(# &2# 51(H'2&"# (2,G%)$-"# :# 2>)*"--$4%# &2# -/%/-$,$2%)/# 2%# *23/($)/*$/(# &/-',2%)"62(# 2>)2%(/(?# 5"N/# *2H'$($)/(# &2# -/%+$&2%-$"6$&"&#:#3*/)2--$4%#&2#&")/(< P'"-+")$7'*%+"B'"B+%;*"+"-+"B'%'@@)/$" B'"*'O+-'*G"'%+0+*"B'")$%'7&+@)/$" +-7;&M%=)@+ n%"#+/*,"#1)$6#&2#&2(-*$5$*#6"#$%-/*3/*"-$4%# &2# EM#"# 6"#&2)2--$4%#&2#(2D"62(#2(#,2&$"%)2# 2)"3"(#2%-"&2%"&"(<#!"#3*$,2*"#-/**2(3/%0 &2#"#6"#$%72()"#:#%/*,"6$;"-$4%#&2#&")/(?#$%0 -6':2%&/# 6$,3$2;"?#-/%)*/6#&2#&'36$-$&"&2(?# "*,/%$;"-$4%#&2#+/*,")/(#:#2()"%&"*$;"-$4%# farmacovigilancia 72 FARMESPAÑA INDUSTRIAL · MAY/JUN 26